• BACT/ALERT Culture Media
  • BACT/ALERT Culture Media

BACT/ALERT® Culture Media

Provides an optimal environment for the recovery of a wide range of organisms, including bacteria, fungi and mycobacteria

  • Flexible media recovers organisms from many sample types from blood to sterile body fluids
  • Colorimetric technology and sophisticated algorithms minimize false negatives
  • Standard and specialized Fastidious Antimicrobial Neutralization media available
  • Shatter-proof plastic bottles maximize safety without compromising performance

Colorimetric detection outshines other technology

With colorimetric detection, BACT/ALERT® culture media offers you sophisticated technology that outshines the rest. Specialized Liquid Emulsion Sensors (LES) at the bottom of each culture bottle visibly change color when the pH changes due to the rise in CO2 as it is produced by microorganisms. BACT/ALERT® 3D instruments measure the color changes every ten minutes and analyze the changes. Sophisticated algorithms, including a unique “threshold” algorithm, ensure early detection of micro-organisms. Even when bottles are delayed in transit, the visual color change helps you potentially identify positive bottles prior to entry into the system. That’s how you can be assured of accurate detection and rapid recovery of microorganisms from various sample types.

  • Technology and sophisticated algorithms help minimize false negatives due to delayed entry
  • Low false-positive rates
  • Visual, irreversible color change

 

Flexible media delivers reliable recovery

BACT/ALERT® culture media offers a comprehensive range of media bottles to ensure the rapid recovery of a wide variety of microorganisms including bacteria, mycobacteria, fungi, and yeasts. From various sample types including blood, sterile body fluids and sputum, BACT/ALERT® culture media can detect 98% of isolates within 72 hours*.

  • FDA-cleared for blood, sterile body fluids and platelets
  • Recovers a wide range of microorganisms
  • Specialized bottles for mycobacterium recovery
  • Fastidious Antimicrobial Neutralization media optimizes recovery for patients on antimicrobial therapy
*Bourbeau PP and Pohlan JK.
*Three days of incubation may be sufficient for routine blood cultures with BACT/ALERT® FAN® blood culture bottles. J Clin Microbiol. 2001; 39(6): 2079-82.

 

New FAN® Plus media: optimized time to detection and recovery

Our next generation Fastidious Antimicrobial Neutralization Plus media (FAN® Plus) offers optimized time to detection and recovery. FAN® Plus bottles provide even clearer Gram stains and new Adsorbent Polymeric Beads offer antimicrobial neutralization.

  • Optimized Microorganism Recovery
    • Reformulated media provide a robust environment that encourages microbial growth for bacteria and yeasts
    • Effective organism growth in blood and sterile body fluids
    • Growth performance guidelines under delayed entry conditions
  • Optimized Time To Detection
    • Effective antimicrobial neutralization provides better environment for organism growth and detection

Safety & efficiency: trust the pioneer in plastic collection bottles

bioMérieux was the first to introduce revolutionary multilayer plastic bottles. Made of unique polycarbonate material, their triple-layer design ensures appropriate environment for recovery of microorganisms. These shatter-resistant bottles significantly improve safety in the laboratory by eliminating accidental spills, potential biohazard exposure and glass cuts. Because they weigh less, these bottles have the added benefit of reducing shipping and disposal costs. And – as numerous studies have shown – the bottom line is that you get all these clear advantages while still ensuring optimal performance in recovery and time to detection.

  • Shatter-resistant bottles reduce potential for biohazard exposure
  • Up to 2/3 lighter than glass
  • Cost-effective storage, shipping and disposal
  • Multi-layer, gas-impermeable design maintains aerobic or anaerobic environments
  • Adapt to a variety of protocols and enable pneumatic transport without a special container

 

 

Standard Media

  Bottle Type Media Formulation Specimen Type Specimen Volume

BACT/ALERT® SA
Standard Aerobic
- Ref. 259789

40 ml supplemented tryptic soy broth (TSB) 

Blood or normally sterile body fluid (SBF)

Up to 10 ml

BACT/ALERT® SN
Standard Anaerobic
- Ref. 259790

40 ml TSB Blood or SBF Up to 10 ml

 

Fastidious Antimicrobial Neutralization Plus Media (FAN® Plus)

  Bottle Type Media Formulation Specimen Type Specimen Volume

BACT/ALERT® FA Plus
- Ref. 410851

30 ml of  supplemented complex media containing adsorbent polymeric beads 

Blood or normally sterile body fluid (SBF)

Up to 10 ml

BACT/ALERT®
FN Plus

- Ref. 410852

40 ml of  supplemented complex media containing adsorbent polymeric beads 

Blood or SBF Up to 10 ml
 

BACT/ALERT® PF Plus
- Ref. 410853

30 ml of  supplemented complex media containing adsorbent polymeric beads 

Blood Up to 4 ml

 

Mycobacterium Media

  Bottle Type Media Formulation Specimen Type Specimen Volume
BACT/ALERT® MP Mycobacteria Process -
Ref. 259797 Use with ref. 259760
10 ml supplemented Middlebrook 7H9 broth. Processed specimen or SBF other than blood. 0.5 ml

 

Platelet QC Testing

  Bottle Type Media Formulation Specimen Type

Speci

men Volume

BACT/ALERT®
BPA Aerobic Platelet culture bottles
– Ref. 279018
or
EU Ref
. 279044
40 ml supplemented tryptic soy broth (TSB) Leukocyte reduced apheresis platelet (LRAP ) units, and both leukocyte reduced single and a pool of up to six (6) units of leukocyte reduced whole blood platelet concentrates (LRWBPC) 4 – 10 ml
BACT/ALERT®
BPN Anaerobic Platelet culture bottles
Ref. 279019
or
EU Ref
. 279045
40 ml supplemented tryptic soy broth (TSB) Leukocyte reduced apheresis platelet (LRAP ) units, and both leukocyte reduced single and a pool of up to six (6) units of leukocyte reduced whole blood platelet concentrates (LRWBPC) 4 – 10 ml

 

Greiner Bio-One VACUETTE® Safety Blood Collection Sets and Bulk Adapter*

  Description Product # Packaging
VACUETTE® Safety Blood Collection Sets 
Contains needle, tubing and Greiner adapter in sterilized packet.

 

Ref. 413251 - Needle Size 21G, 30cm tubing. Ref. 413201 - Needle Size 23G, 30cm tubing. Ref. 415419 - Needle Size 21G, 19cm tubing. Ref. 415450 - Needle Size 23G, 19cm tubing.

 

240 per case

Bulk non sterile adapter 
Non-sterile adapter cap with improved neck design to accommodate evacuated tubes without the need for an insert. (Female threaded Luer).
Ref. 413200 320 per case 
 

 

COVIDIEN Products 

  Description  Product Number

covidien_-_ca006.jpg

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MonojectTM Collection Device, Male

The MonojectTM collection device is a single use device for the collection of blood specimens 

 

Ref. CA006

covidien_411350.jpg

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MonojectTM Transfer Device, Female 

The MonojectTM transfer device is single use for safe transfer of blood specimen from a syringe into a blood culture bottle

 

Ref. 411350               

 

Safety SubCulture Units 

  Description  Product Numbe

saferty_subculture_unit.jpg

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Safety SubCulture Unit 

Safe, needleless transfer of samples from positive blood-culture bottles 

 

Ref. 419142

 

For product availability, please contact your local bioMérieux representative. 

 

BACT/ALERT® VIRTUO® & BACT/ALERT® FAN® PLUS MEDIA PUBLICATIONS 

BACT/ALERT® VIRTUO®

Miller N, Brassinne L, Allemeersch D. Implementation of the new VIRTUO blood culture system: evaluation and comparison to the 3D system using simulated blood cultures. Acta Clinica Belgica 2018;73(1):16-2

 

She R.C., Romney M.G., Jang W., Walker T., Karichu J.K., Richter S.S. Performance of the BACT/ALERT VIRTUO Microbial Detection System for the culture of sterile body fluids: prospective multi-centre study. Clinical Microbiology And Infection 2018;24(9):992-996

 

Jacobs M.R., Mazzulli T., Hazen K.C., Good C.E., Abdelhamed A.M., Lo P., Shum B., Roman K.P., Robinson D.C. Multicenter Clinical Evaluation of BACT/ALERT VIRTUO Blood Culture System. Journal of Clinical Microbiology 2017;55(8):2413-2421.

 

Totty H., Ullery M., Spontak J., Viray J., Adamik M., Katzin B., Dunne WM Jr., Deol P. A controlled comparison of the BACT/ALERT 3D and VIRTUO™ microbial detection systems. European Journal of Clinical Microbiology 2017;36(10):1795-1800

 

BACT/ALERT® FAN® PLUS MEDIA vs. BACTEC™

Lovern D., Katzin B., Johnson K., Broadwell D., Miller E., Gates A., Deol P., Doing K., van Belkum A., Marshall C., Mathias E., Dunne WM Jr. Antimicrobial binding and growth kinetics in BACT/ALERT FA PLUS and BACTEC Aerobic/F Plus blood culture bottles. European Journal of Clinical Microbiology and Infectious Diseases 2016; 35(12):2033-2036.      

 

Fiori B., D’Inzeo T., Di Florio V., De Maio F., De Angelis G., Giaquinto A., Campana L., Tanzarella E., Tumbarello M., Antonelli M., Sanguinetti M., and Spanu T.  Performance of Two Resin-Containing Blood Culture Media in Detection of Bloodstream Infections and in Direct Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry (MALDI-TOF MS) Broth Assays for Isolate Identification: Clinical Comparison of the BACT/ALERT Plus and BACTEC Systems. Journal Of Clinical Microbiology 2014; 52(10): 3558-3567

 

 

BACT/ALERT® FAN® PLUS MEDIA vs. BACT/ALERT® FAN AND STANDARD MEDIA

Amarsy-Guerle R., Mougari F., Jacquier H., Oliary J., Benmansour H., Riahi J., Berçot B., Raskine L., Cambau E. High medical impact of implementing the new polymeric bead-based BACT/ALERT FA PLUS and FN PLUS blood culture bottles in standard care. European Journal of Clinical Microbiology & Infectious Disease 2015;34(5):1031-7.

Pioneering diagnostics